Migrane Pain & symptoms

A migraine headache is mostly described by the case as a forceful pounding pain involving one temple. In some instances, the pain is bring into being in the forehead, nearby one eye, or in the back of the ego's head. Normally the pain is said to be joint, meaning it affects only one side of the head, although it can affect both sides in round a third of the cases. It's unusual for these headaches to change sides, basic striking one side, and then on the next attack, affecting the further side. Some common symptoms of migraines add in vomiting, unsettled stomach, diarrhea, cold hands and feet, mudpack whiteness, and a thoughtfulness to unassailable and light.

What is a Migraine Headache?

A migraine is a persistent, throbbing headache typically affecting one side of the head. It can last from anywhere between 4 and 72 hours. Migraines are thought to be caused by a precipitous splayed of the genealogy vessels that provision the brain, which in turn irritates the stress surrounding these lifeblood vessels.

Migraine Headache Symptoms

Migraine headaches can be accompanied by symptoms that have a weighty control on diurnal life. As well as the headache, relatives may also experience symptoms such as motion sickness, vomiting and imagistic disturbances. Occasionally, symptoms can be more rigorous - including one-sided paralysis, exertion in speaking, commotion, or fainting. (See Migraine Headache Symptoms)

Migraine Headache Causes:

The faithful causes of migraine headaches are not completely unspoken, but you may find that undeniable triggers can start or worsen a migraine. Avoiding these migraine triggers can become an effective revenue of reducing the digit of attacks.

Depression or adjustment disorder with depressed mood?

In the presence of depressed mood accompanied by symptoms, diagnoses of major depression or adjustment disorder with depressed mood may be performed.

The diagnosis of adjustment disorder applies when the depressed mood and other symptoms develop in response to a stressful situation and that the diagnostic criteria of major depression are not met. When the criteria for major depression are met, the latter diagnosis prevails.

Here are the diagnostic criteria of major depression according to DSM IV (1):
At least five of the following symptoms have been present for a period of at least two weeks, at least one of these symptoms is either (1) depressed mood or (2) loss of interest or pleasure.

1. Depressed mood most of the day, nearly every day, as indicated by the subject or observed by others.
2. Markedly diminished interest or pleasure in all or almost all activities almost all day almost every day.
3. loss or significant weight gain in the absence of regime, or decrease or increase in appetite nearly every day.
4. Insomnia or hypersomnia nearly every day.
5. psychomotor agitation or retardation nearly every day (observable by others, not limited to subjective feelings of restlessness or being slowed down).
6. Fatigue or loss of energy nearly every day.
7. Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick).
8. Diminished ability to think or concentrate or indecisiveness, nearly every day.
9. Recurrent thoughts of death (not just fear of dying) recurrent suicidal ideation without a specific plan or suicide attempt or specific plan for committing suicide.

The criteria of adjustment disorder:

A. Development of symptoms in the emotional and behavioral records, in response to one or more factor (s) identified stress (s) during the three months following the occurrence of it (them).

B. These symptoms or behaviors are clinically significant, as evidenced by:

• a marked distress, higher than was expected in response to stressors
• a significant impairment in social or occupational (or school).

C. The stress-related disturbance does not meet criteria for another disorder (for example, major depression, post traumatic stress disorder, acute stress disorder) and is not merely an exacerbation of a preexisting condition (for example, a personality disorder).

D. The symptoms are not an expression of mourning.

E. Once the stressor (or its consequences) has disappeared, the symptoms do not persist beyond 6 months.

The DSM IV identifies six subtypes of the disorder, an adaptation that are determined by the most predominant symptoms:

• With Depressed Mood
• With anxiety
• With both anxiety and depressive mood
• With Disturbance of Conduct
• With disruption of both emotions (depression, anxiety) and behavior
• Unspecified

Migraines: still a matter of hormones?

Faced with migraines, female vulnerability appears to be related to hormonal changes. In the dock, the secretion of estrogen, which varies during the cycle. The best evidence is the frequency of migraine called "catamenial, which occur over the rules or in the two days that precede them.

Why give estrogen migraine

Affecting 5 to 8% of women, these periodic headaches coincide with the sharp drop in estrogen that triggers the rules. They can be prevented by percutaneous application of estrogen.

Other evidence argue for the involvement of hormonal fluctuations. Thus women with migraines have almost always an improvement of their headaches during pregnancy and migraine tends to become less common after menopause.

Mechanism by which these hormones can they influence the occurrence of migraines? In an attempt to uncover this mystery, researchers at the University of Kansas artificially reproduced in mice phenomena vascular origin of migraine auras, that is to say that visual signs sometimes precede the migraine pain. They just presented their findings at the Congress of the American Academy of Neurology.

More than a thousand genes studied

The experiment was conducted on three groups of mice:

• Male mice;
• Female mice without ovaries (thus devoid of estrogen);
• Female mice without ovaries, but treated with estrogen.
  

Potassium chloride was administered into the brains of these animals to produce the electrical phenomena characteristic auras. The researchers then analyzed the expression of over a thousand genes. They have seen and, in males as in females without ovaries, some genes were activated and others inhibited, to mitigate the adverse effects of electrical damage.

In female mice treated with estrogen the same genes were modulated, but in an opposite direction, resulting in the secretion of substances with property to reduce inflammation and vascular dilatation responsible for migraine pain. Conversely, we can assume that the sharp decrease of secretion of this hormone during menstruation, promote changes in vascular origin of migraine. However, it should be noted that these results were obtained in experimental conditions far removed from migraine, especially catamenial forms that occur most often without aura ...

Runway magnesium

Researchers in New York have sought for their part, the presence of an ionized magnesium deficiency in 61 women with catamenial migraines *. They have seen and the deficit was more frequent (45% of cases) during the catamenial migraine, and during menstruation without migraine (14%) for non-menstrual migraine (15%) or between periods (15 %).

These results suggest that magnesium deficiency may play a role in some forms of menstrual migraine. They require however to be confirmed on a larger number of patients.

Head of the first study, Professor Loretta Mueller said that "75% of migraine sufferers are women and over half reported a hormonal origin. But we still do not know if we need to treat these headaches differently from men. Further studies may be able to answer ...